Directly utilizing an endogenous gene to dissect regulatory elements in the biosynthetic gene cluster of nosiheptide.
نویسندگان
چکیده
The regulatory elements for nosiheptide biosynthesis were identified by a novel host-vector system with an endogenous gene within the biosynthetic gene cluster as a reporter gene. The present study offers a rapid and reliable method for the identification of regulatory elements in the biosynthesis of various bioactive natural products.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 72 شماره
صفحات -
تاریخ انتشار 2014